Poster No:
633
Submission Type:
Abstract Submission
Authors:
Kaie Habata1, Daichi Shiotsu2, Kotaro Kowada2, Taku Kamiya2, Takuya Makino3, Riku Sanada2, Masatoshi Yamashita4, Yoshifumi Mizuno4, Hidehiko Okazawa5, Bae Jihyun6, Jung Minyoung6, Hirotaka Kosaka7
Institutions:
1Department of Neuropsychiatry, University of Fukui, Eiheiji, Fukui, Japan, 2Department of Neuropsychiatry, University of Fukui, Eiheiji, Fukui, 3Department of Neuropsychiatry, University of Fukui, Eiheiji, Fukui, 4Research Center for Child Mental Development, University of Fukui, Eiheiji, Fukui, 5Biomedical Imaging Research Center, University of Fukui, Eiheiji, Fukui, 6Cognitive Science Research Group, Korea Brain Research Institute, Daegu, Daegu, 7University of Fukui, Fukui, NA
First Author:
Kaie Habata
Department of Neuropsychiatry, University of Fukui
Eiheiji, Fukui, Japan
Co-Author(s):
Daichi Shiotsu
Department of Neuropsychiatry, University of Fukui
Eiheiji, Fukui
Kotaro Kowada
Department of Neuropsychiatry, University of Fukui
Eiheiji, Fukui
Taku Kamiya
Department of Neuropsychiatry, University of Fukui
Eiheiji, Fukui
Takuya Makino
Department of Neuropsychiatry, University of Fukui
Eiheiji, Fukui
Riku Sanada
Department of Neuropsychiatry, University of Fukui
Eiheiji, Fukui
Masatoshi Yamashita
Research Center for Child Mental Development, University of Fukui
Eiheiji, Fukui
Yoshifumi Mizuno
Research Center for Child Mental Development, University of Fukui
Eiheiji, Fukui
Hidehiko Okazawa
Biomedical Imaging Research Center, University of Fukui
Eiheiji, Fukui
Bae Jihyun
Cognitive Science Research Group, Korea Brain Research Institute
Daegu, Daegu
Jung Minyoung
Cognitive Science Research Group, Korea Brain Research Institute
Daegu, Daegu
Introduction:
The amygdala is thought to be associated with the perception of self body image. Recent studies have indicated that the amygdala is functutionally abnormal in patients with eating disorders, such as anorexia nervosa (AN), which involves body image disturbance (Burkert et al., 2019). We hypothesized that the amygdala would be associated with body image disturbance, and we explored the correlation between resting-state neural activity in each limbic region, including the amygdala, and subjective evaluations of body image.
Methods:
Thirty adolescent healthy females were included in this study. Participants also provided subjective self-ratings of body image using the Basic Olomouc Body Rating (BOBR) scale (Šrámková et al., 2015), consisting of ten body image silhouettes representing different BMI (Body Mass Index) values. The degree of body image distortion was determined by calculating the difference between the participant's actual image and ideal image corresponding to their subjective self-selected body image silhouette. 3-Tesla MRI scans were performed, and functional connectivity analyses, seed to voxel analysis were carried out using the CONN-fMRI functional connectivity toolbox. Limbic regions (thalamus, caudate, putamen, pallidum, hippocampus, amygdala, accumbens nucleus) were selected as seed.
Results:
Negative correlations with the degree of body image gap were shown for the connectivity with the right amygdala and temporal pole gyrus (p<0.00001).
Conclusions:
Activation of the amygdala has been shown to play an important role in the emotional body evaluation of AN patients when they see distorted images of their own bodies (Seeger et al., 2002). In this study, we evaluated he relationship between body image gap and resting-state brain connectivity in limbic regions. The relationship between body image gap and amygdala activity reflected distorted perception of body image, suggesting that the amygdala may play an important role in body image even in healthy subjects.
Disorders of the Nervous System:
Psychiatric (eg. Depression, Anxiety, Schizophrenia) 1
Emotion, Motivation and Social Neuroscience:
Emotional Perception
Modeling and Analysis Methods:
Connectivity (eg. functional, effective, structural) 2
Novel Imaging Acquisition Methods:
BOLD fMRI
Keywords:
Eating Disorders
Limbic Systems
MRI
Other - Amygdala
1|2Indicates the priority used for review
Provide references using author date format
Burkert. (2019), 'Body image disturbances, fear and associations with the amygdala in anorexia nervosa', Wien. Klin. Wochenschr., vol. 131, no. 3-4, pp. 61-67
Seeger. (2002), 'Body image distortion reveals amygdala activation in patients with anorexia nervosa -- a functional magnetic resonance imaging study', Neurosci, vol. 326, no. 1, pp. 25-28