Social jetlag and habitual short sleep duration affect neural reward function
Poster No:
768
Submission Type:
Abstract Submission
Authors:
Shuo Wang1, Yun Tian1, Ruyue Xie1, Hanfei Chen1, DeXu Yin1, Huimin Duan1, xu lei1
Institutions:
1Southwest University, Chongqing, China
First Author:
Co-Author(s):
Introduction:
Although social jetlag was indeed found to affect reward function in previous studies, these studies often confounded the effects of social jetlag (SJL) and habitual short sleep duration on reward dysfunction. Therefore, the present study focused on the different effects of social jetlag and habitual short sleep duration on reward function.
Methods:
Sixty-three college students were enrolled in 4 study groups according to the presence of SJL and habitual short sleep duration (2 groups with SJL with or without habitual short sleep duration and 2 groups without SJL without habitual short sleep duration). They completed a functional magnetic resonance imaging scan using a gambling risk task and self-reported questionnaires. Region-interest analyses focused on the medial prefrontal cortex (mPFC) and striatum both of which are implicated reward function. Analyses adjusted gender, age, Body mass index (BMI) and chronotype scores.
Results:
In the reward anticipation phase, between-group differences were found only in the whole-brain action analysis, and no intergroup differences were found in the two regions of interest (GRF correction, the cluster-level: P < 0.05; two-tailed, with voxel level P < 0.005). Post hoc analyses showed that the habitual short sleep duration group exhibited significantly increased activation in the right superior occipital gyrus and right middle occipital gyrus compared to the control group (Figure 1A). Compared to the control group, the social jetlag group showed significantly increased activation in the right superior occipital gyrus, right middle occipital gyrus, and right superior parietal gyrus (Figure 1B). The difference in activation between the control group and the habitual short sleep duration co-social jetlag group was not significant. Compared to both the habitual short sleep duration and social jetlag groups, the habitual short sleep duration co-social jetlag group exhibited significant reductions in activation in the left dorsolateral prefrontal cortex, left medial frontal gyrus, and left orbital part of the middle frontal gyrus (Figure 1C).
·Figure 1. Intergroup differences in the analysis of whole brain activity during reward anticipation (colored bars reflect t scores for each analysis)
Conclusions:
In addition to habitual short sleep duration and social jetlag, the habitual short sleep duration co-social jetlag can lead to mood changes and change in reward and punishment sensitivity, and these changes in cognitive function may be due to impaired neural reward function. Further neuroimaging results corroborate this finding.
Emotion, Motivation and Social Neuroscience:
Reward and Punishment 1
Modeling and Analysis Methods:
Activation (eg. BOLD task-fMRI) 2
Keywords:
FUNCTIONAL MRI
Sleep
Other - Social jetlag; habitual short sleep duration; gambling risk task
1|2Indicates the priority used for review
Provide references using author date format
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