Determinations of Organic Ultraviolet (UV) Filters in Consumer Products by SPME-GC-MS/MS
Abstract No:
1265
Abstract Type:
Professional Poster
Authors:
M KAO1
Institutions:
1NATIONAL TAIWAN UNIVERSITY, TAIPEI, TAIWAN
Presenter:
MING CHUN KAO
NATIONAL TAIWAN UNIVERSITY
NATIONAL TAIWAN UNIVERSITY
Description:
Organic ultraviolet (UV) filters are widely used in consumer products. Some studies have indicated that UV filters may cause endocrine disrupting or other harmful health effects. To estimate UV filter exposures, there is a need to quantify the levels in various consumer products. In this study, an environment friendly and easily operated method for the determinations of these UV filters was established. With this information on the UV filter distribution in consumer products, the health risks associated with exposures can be assessed in the future.
Situation / Problem:
Organic UV filters are added to consumer products (e.g., sunscreens, personal care products (PCPs), cleansing supplies) to protect the skin against UV radiation or to prevent the products from light-induced degradation. However, UV filters have been: a) identified as possible endocrine disrupting chemicals (EDCs); and b) detected in environmental matrices and human bodies. The information regarding the distributions of UV filters in various categories of products is still limited. Thus, there is a need to establish a suitable method to estimate potential harmful exposures.
Methods:
This study focused on nine compounds commonly used as UV filters: a) Benzophenone-1 (BP-1), b) Benzophenone-3 (BP-3), c) Benzophenone-8 (BP-8), d) Ethylhexyl Salicylate (EHS), e) Homosalate (HMS), f) Octyl Methoxycinnamate (OMC), g) Octocrylene (OC), h) 4- Methylbenzylidene camphor (4-MBC) and i) Avobenzone. All chemicals were dissolved in methanol as the standard solution. Solid-phase microextraction (SPME) combined sampling, extraction and preconcentration into one single step. The samples were diluted by water and equilibrated for 4 minutes before the extraction at 50°C for 30 minutes at 500 rpm. The 50/30 µm divinylbenzene-carboxen-polydimethylsiloxane (DVB/CAR/PDMS) fiber was exposed to the headspace over the samples. After adsorption equilibrium had been reached, the SPME fiber was inserted into the injector of the gas chromatography with tandem mass spectrometry (GC/MS/MS) for thermal desorption and further analysis.
Results / Conclusions:
The headspace SPME procedure coupled with GC/MS/MS analysis for the determinations of UV filters in consumer products was established in this study. The 50/30 µm DVB/CAR/PDMS fiber provided a good extraction efficiency of the UV filters in several kinds of samples. No carryover effect was observed from the thermal desorption of the sample. The linear ranges of these substances ranged from 0.1 to 500 ng ml-1, depending on their properties. Good linearity and precision were presented. The SPME procedure has advantages (e.g., time saving and solvent free) over conventional methods. The sensitivities of the method for different compounds were low enough for measurements. The UV filter concentrations of more than 50 consumer products were determined and assessed for potential health risk associated with exposures.
Primary Topic:
Sampling and Analysis
Secondary Topics:
Risk Assessment and Management
Co-Authors
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Acknowledgements and References
List any additional people who worked on the project or provided guidance and support along with details on the role they played in the research. (Please include first name, last name, organization, city, state and country).
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